Welcome - Urea Cycle Disorders (UCD) Community

What is Urea Cycle Disorders (UCD) ?

A urea cycle disorder is a genetic disorder caused by a mutation that results in a deficiency of one of the six enzymes in the urea cycle. These enzymes are responsible for removing ammonia from the blood stream.

The six urea cycle disorders are:

  • Arginase Deficiency (AG)
  • Argininosuccinic Aciduria (ASA)
  • Carbamyl Phosphate Synthetase Deficiency (CPS)
  • Citrullinaemia
  • N-Acetylglutamate Synthetase Deficiency (NAGS)
  • Ornithine Transcarbamylase Deficiency (OTC)
Urea Cycle Disorders (UCD) Resources

More members stories

Latest Member Stories

MY STORY, OTC.

by saraderiu99 published 4 months ago
2 comments

My name is Sara and in a few days I'll turn eighteen.
I suffer from a disease belonging to the group of Urea Cycle disorders, OTC.
At birth I lo...

Sarah’s Story - OTC

by RareConnect team published 6 months ago
No comment

Growing up with this condition wasn’t always easy as I was often ill and had to be admitted into hospital, I had to take medication and always watc...

Partners and Patient Groups

RareConnect is a patient-led initiative. Patient organisations partner with EURORDIS, itself an international patient organisation, to create communities and provide moderators from within their network. The following patient groups are official partners of this community.