Welcome - Urea Cycle Disorders (UCD) Community

What is Urea Cycle Disorders (UCD) ?

A urea cycle disorder is a genetic disorder caused by a mutation that results in a deficiency of one of the six enzymes in the urea cycle. These enzymes are responsible for removing ammonia from the blood stream.

The six urea cycle disorders are:

  • Arginase Deficiency (AG)
  • Argininosuccinic Aciduria (ASA)
  • Carbamyl Phosphate Synthetase Deficiency (CPS)
  • Citrullinaemia
  • N-Acetylglutamate Synthetase Deficiency (NAGS)
  • Ornithine Transcarbamylase Deficiency (OTC)
Urea Cycle Disorders (UCD) Resources

More members stories

Latest Member Stories

My OTC Story

by ceren published 16 days ago
No comment

Hi :) My name is Ceren , 22 years old, from Turkey. I have an otc since diagnosed when i was 13 months babyhood. My diagnosed determined with when ...

OTC deficiency

by coniugataduefigli published 16 days ago
One comment

It seemed like everything was alright.
A nice 8 year old son, good at school and good at sports.
During Christmas holidays, my son is vomiting a...

Partners and Patient Groups

RareConnect is a patient-led initiative. Patient organisations partner with EURORDIS, itself an international patient organisation, to create communities and provide moderators from within their network. The following patient groups are official partners of this community.