Trimethylaminuria (TMAU) Community

Meet, discuss & support other patients or families living with Trimethylaminuria (TMAU). Contribute to topics, or just share what's on your mind


PH Balance soaps

One of the suggestions on The trimethylaminuria paper published on the NIH Gene reviews site, by Drs. Phillips and Shephard, London, for a TMAU (trimethylaminuria) management protocol is the use of an acid soap/cleanser to attempt to neutralize some of the highly alkaline trimethylamine. For this reason this list is published, until a more comprehensive one can be found.

Trimethylamine is a strong base (pKa 9.8). Thus, at pH 6.0, less than 0.02% of trimethylamine exists as the volatile free base. The use of soaps and body lotions with a pH close to that of normal skin (pH 5.5-6.5) helps retain secreted trimethylamine in a less volatile salt form that can be removed by washing.

Read the full list here:

What is this treatment compared to chlorophyll? Is it possible that in Italy, this does not work at all? I also want to talk to someone in Italian ......