Hi. I am the mother of 2 children with FMF. Our son was diagnosed at 7 yrs old, and prescribed Colchicine along with Phenobarbitol (to control the side effects of Colchicine). The doctor started him on a dosage of .6 mg and to increase at intervals. We noticed that when he began the medication he began to urinate more frequently right away. We were told that he would have bladder spasms due to the medication and that the Phenobarb would control these effects. When his dosage of Colchicine went up to .9mg, he became incontinent. I was told by the doctor and manufacturer that Colchicine has never caused this to happen before or at least its never been reported in (child) patients before. It's been over a year since he began treatment for FMF. And he is still taking medication for FMF (Colcrys 1.2 mg) and Oxybutnin 10mg ER for the incontinence and side effects of Colchicine. My question is, has anyone else experienced this kind of side effect of the drug? And our son's Urologist isn't sure what to expect since he's never treated a child with FMF. Will the incontinence resolve as he gets older, or adjusts to the medication? Any info is appreciated. Thank you.
Tauna